Topic: research
VACCINE ENHANCEMENTS
Researchers at the Tulane National Primate Research Center found that a vaccine currently being developed induces a robust and long-lasting immune response against SARS-CoV-2 in nonhuman primates, similar to the protection provided by the Moderna vaccine. The study evaluated five different adjuvants, or ingredients added to vaccines, to determine which provides the most protection from the virus in nonhuman primates.https://tulane.it/vaccine-enhancements
WATER SCARCITY FOOTPRINT
Researchers at Tulane and the University of Michigan examined the water-use impacts of individual diets in the United States, while considering regional variations in water scarcity. They found meat consumption is the top contributor to the water scarcity footprint of the average U.S. diet, accounting for 31% of the impacts. The study combines the types and quantities of foods in the diets of individuals, the irrigation water required to produce those foods, and the relative scarcity of water where the irrigation occurs.https://tulane.it/water-scarcity-footprint
SALIVA TEST
Tulane researchers developed a 15-minute saliva-based COVID-19 test that is read by a smartphone. The assay platform developed by Tony Hu, Weatherhead Presidential Chair in Biotechnology Innovation at the School of Medicine, and associates can detect very small amounts of SARS-CoV-2 virus RNA in saliva by leveraging CRISPR, the revolutionary gene editing technology.https://tulane.it/saliva-test
IMMUNE RESPONSE
A study led by Monica Vaccari, associate professor of microbiology and immunology at Tulane National Primate Research Center, suggests that in the early weeks of post-infection of COVID-19, the stronger the initial host immune response, the worse the disease outcome. While the body mounts a pro-inflammatory “innate” immune response as a first line of defense to protect against the spread of infection and heal damaged tissue, it is a dysregulated or over-reactive immune response that can cause severe damage, Vaccari’s study explains.https://tulane.it/immune-response
REOPENING K-12 SCHOOLS
According to a new study by the National Center for Research on Education Access and Choice at Tulane, reopening K-12 schools in the U.S. did not result in an increase in hospitalizations due to COVID-19. Co-authors Douglas Harris, chair of the Department of Economics, and Engy Ziedan, assistant professor of economics, found no evidence that reopening schools in-person or in a hybrid form increased COVID-19 hospitalizations in the 75 percent of counties that had low hospitalization rates during the summer prior to reopening schools.https://tulane.it/reopening-k-12-schools
HARDEST HIT
Tulane will launch an outreach initiative to reach ethnic and racial minority communities in Louisiana that are disproportionately affected by the COVID-19 pandemic. The Louisiana Community Engagement Alliance, of which Tulane is a part, is working with residents, community leaders, health centers, faith-based organizations, pharmacies and the Louisiana Department of Health. The work is being funded by a $1 million grant from the National Institutes of Health. https://tulane.it/hardest-hit
DRUG TREATMENT BOOST
Work on a new COVID-19 drug by a Tulane researcher is getting fast-tracked. Dr. Jay Kolls, a professor of medicine and pediatrics, the John W. Deming Endowed Chair in Internal Medicine, and director of the Center for Translational Research in Infection and Inflammation, has received a $100,000 Fast Grant for his research to create a drug that prevents the COVID-19 virus from entering healthy cells. https://tulane.it/drug-treatment-boost
SUPERSPREADERS
Researchers at Tulane, Harvard, MIT and Massachusetts General Hospital have learned that subjects who were older with higher body mass indexes and an increasing degree of COVID-19 infection had three times the number of exhaled respiratory droplets — key spreaders of SARS-CoV-2, the virus that causes COVID-19 — as others in the study groups. The increase in exhaled aerosols occurred even among those with asymptomatic cases of COVID-19, said Chad Roy, corresponding author and director of infectious disease aerobiology at the Tulane National Primate Research Center. https://tulane.it/superspreaders
CARDIOVASCULAR HEALTH DISPARITIES
Tulane will recruit and train community health workers to implement a comprehensive health and lifestyle coaching program for congregants in predominantly African American churches in New Orleans and Bogalusa, Louisiana, to help eliminate cardiovascular health disparities among African Americans. This work will be funded by a $8.7 million grant from the National Institutes of Health. The program will focus on healthy eating, exercise, weight loss, improving cholesterol numbers, addressing high blood pressure and controlling other risk factors. https://tulane.it/cardiovascular-health-program
