Topic: research

WHAT TRIGGERS STROKES?
For the first time, researchers at Tulane University and Ochsner Health were able to genetically sequence plaque tissue collected from patients within days after a stroke.

MENSTRUAL CHANGES
Katharine Lee, assistant professor of anthropology, co-authored a study that found COVID-19 vaccines affected people’s menstrual periods, especially those who don’t typically have periods due to long-acting contraceptives, gender-affirming hormone treatments or menopause. The study began shortly after vaccines became widely available and individuals reported through social media changes in their menstrual cycles after receiving the vaccines.https://tulane.it/menstrual-changes

VASCULAR EFFECTS
Researchers are investigating the role endothelial cells play in the development of severe and long COVID-19. The cells line blood vessel walls and can malfunction following SARS-CoV-2 infection. This dysfunction can cause blood clotting in organs, as seen in the most severe COVID-19 cases. Dr. Xuebin Qin of the Tulane National Primate Research Center is leading the research. https://tulane.it/vascular-effects

Investigations of the Brain
The Tulane Brain Institute under the leadership of psychology professor Jill Daniel is answering some of the biggest questions in brain science, from aging and estrogen therapy to fear and trauma. The institute involves researchers and students from all parts of the university.

METABOLIC SYNDROME
Patients hospitalized with COVID-19 who had a combination of high blood pressure, obesity, diabetes or other conditions associated with metabolic syndrome were at much higher risk of acute respiratory distress syndrome and death, according to a study published in the medical journal JAMA Network Open. Dr. Joshua Denson, assistant professor of medicine, was the study’s lead author.https://tulane.it/metabolic-syndrome

VIRUSES IN WASTEWATER
The Environmental Protection Agency has awarded a $1.24 million grant to a research team to come up with standards for measuring viruses and other pathogens in treated wastewater for water re-use projects. Samendra Sherchan, associate professor in the Department of Environmental Health Sciences and director of the Water Quality Lab at the School of Public Health and Tropical Medicine, is part of the team.https://tulane.it/viruses-in-wastewater

VIRAL DOSE AND DISEASE SEVERITY
Chad Roy, professor of microbiology and immunology and director of infectious disease aerobiology at the Tulane National Primate Research Center, and Dr. Gregory Bix, professor and vice chair of neurosurgery and neurology, director of COBALT (COVID-19 Biobank and Library at Tulane), and director of the clinical neuroscience research center, were among a team of scientists who co-authored a review of 115 peer-reviewed studies in Clinical Infectious Diseases.https://tulane.it/viral-dose-disease-severity

LESSONS FOR TEACHERS
A study led by Stacy Overstreet, professor of psychology, shows that when the COVID-19 pandemic forced New Orleans public school teachers to switch from in-person instruction to a virtual or hybrid setting, the transition left many feeling anxious over their ability to impact student learning. The study also reveals that many teachers suffered from anxiety, depression and post-traumatic stress. It recommends expansion of access to mental health care, improvement in sick leave and bereavement policies and offering hazard pay.https://tulane.it/lessons-for-teachers

LINGERING IMPACTS ON BRAIN
Tracy Fischer, associate professor of microbiology and immunology at the Tulane National Primate Research Center, led a study published in Nature Communications, investigating how COVID-19 affects the central nervous system. The research team found severe brain inflammation and injury consistent with reduced blood flow or oxygen to the brain, including neuron damage and death. Microhemorrhages, or small bleeds in the brain, were also present. Surprisingly, these findings were seen in subjects that did not experience severe respiratory disease from the virus.https://tulane.it/lingering-impacts

ZOONOTIC DISEASE
Hannah Frank, an assistant professor in ecology and evolutionary biology and bat expert, is sharing in a $1.25 million award with scientists from other universities to study how to mitigate zoonotic threats. Zoonotic disease — diseases from non-humans that can infect humans — are an increasing problem and threat to human health and well-being. Bats are a particularly important group to understand because they can spread and shed infections including SARS-CoV-2, which do not cause disease in bats but are highly lethal to humans and other animals.https://tulane.it/zoonotic-disease